ADAMTSL2 Antikörper (AA 522-580) (Biotin)
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- Target Alle ADAMTSL2 Antikörper anzeigen
- ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
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Bindungsspezifität
- AA 522-580
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ADAMTSL2 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ADAMTSL2
- Isotyp
- IgG
- Top Product
- Discover our top product ADAMTSL2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- ADAMTSL2 (ADAMTS-Like 2 (ADAMTSL2))
- Andere Bezeichnung
- ADAMTSL2 (ADAMTSL2 Produkte)
- Synonyme
- ADAMTSL2 antikoerper, GPHYSD1 antikoerper, A930008K15Rik antikoerper, tcp-1 antikoerper, RGD1305459 antikoerper, ADAMTS-like 2 antikoerper, ADAMTS like 2 antikoerper, ADAMTS-like protein 2 antikoerper, ADAMTSL2 antikoerper, adamtsl2 antikoerper, LOC100589493 antikoerper, Adamtsl2 antikoerper
- Hintergrund
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Synonyms: ADAMTS like 2, ADAMTS like protein 2, ADAMTS-like protein 2, ADAMTSL 2, ADAMTSL-2, ADAMTSL2, ATL2_HUMAN.
Background: ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.
- Gen-ID
- 9719
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