Kallikrein 8 Antikörper (AA 51-150)

Produktnummer ABIN759116

Produktdetails anti-Kallikrein 8 Antikörper

Target: Kallikrein 8 (KLK8)

Bindungsspezifität: AA 51-150

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse KLK8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Kallikrein 8 Antikörper (ABIN759116)

Hadamitzky, Herring, Kirchhof, Bendix, Haight, Keyvani, Lückemann, Unteroberdörster, Schedlowski: "Repeated Systemic Treatment with Rapamycin Affects Behavior and Amygdala Protein Expression in Rats." in: The international journal of neuropsychopharmacology, Vol. 21, Issue 6, pp. 592-602, (2019) (PubMed).

Details zu Kallikrein 8

Target: Kallikrein 8 (KLK8)

Andere Bezeichnung: KLK8 (KLK8 Produkte)

Synonyme: HNP antikoerper, NP antikoerper, NRPN antikoerper, PRSS19 antikoerper, TADG14 antikoerper, bsp1 antikoerper, KLK8 antikoerper, BSP1 antikoerper, Nrpn antikoerper, Prss19 antikoerper, kallikrein related peptidase 8 antikoerper, kallikrein related-peptidase 8 antikoerper, KLK8 antikoerper, Klk8 antikoerper

Hintergrund:

Synonyms: BSP1, Nrpn, Prss19, Kallikrein-8, mK8, Neuropsin, NP, Serine protease 19, Klk8

Background: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.

Gen-ID: 259277

UniProt: Q61955

Pathways: Komplementsystem