desert Hedgehog Antikörper (AA 101-200)

Produktnummer ABIN759686

Der Kaninchen Polyklonal Anti-desert Hedgehog-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p) validiert. Er ist geeignet, desert Hedgehog in Proben von Maus zu detektieren.

Kurzübersicht für desert Hedgehog Antikörper (AA 101-200) (ABIN759686)

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser desert Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-desert Hedgehog Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Andere Bezeichnung: DHH

Substanzklasse: Species

Hintergrund:

Synonyms: Desert hedgehog Drosophila homolog, Desert hedgehog, Desert hedgehog homolog Drosophila, Desert hedgehog protein precursor.

Background: This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N terminal portion is soluble and contains the signalling activity while the C terminal portion is involved in precursor processing. More importantly, the C terminal product covalently attaches a cholesterol moiety to the N terminal product, restricting the N terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Gen-ID: 50846

Pathways: Hedgehog Signalweg