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PLAG1 Antikörper

PLAG1 Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN760526
  • Target Alle PLAG1 Antikörper anzeigen
    PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
    Reaktivität
    • 45
    • 33
    • 18
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 57
    • 3
    Kaninchen
    Klonalität
    • 58
    • 2
    Polyklonal
    Konjugat
    • 16
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PLAG1 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 19
    • 12
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PLAG1
    Isotyp
    IgG
    Top Product
    Discover our top product PLAG1 Primärantikörper
  • Applikationshinweise
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
    Andere Bezeichnung
    Plag1 (PLAG1 Produkte)
    Synonyme
    PLAG1 antikoerper, MGC152687 antikoerper, PSA antikoerper, SGPA antikoerper, ZNF912 antikoerper, PLAG1 zinc finger antikoerper, pleiomorphic adenoma gene 1 antikoerper, PLAG1 antikoerper, plag1 antikoerper, Plag1 antikoerper
    Hintergrund

    Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

    Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

    Gen-ID
    5324
    UniProt
    Q6DJT9
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