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ASAH2 Antikörper (AA 701-780)

ASAH2 Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN761276
  • Target Alle ASAH2 Antikörper anzeigen
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    Bindungsspezifität
    • 9
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    AA 701-780
    Reaktivität
    • 32
    • 14
    • 5
    Human
    Wirt
    • 33
    • 1
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASAH2 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 20
    • 5
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ASAH2
    Isotyp
    IgG
    Top Product
    Discover our top product ASAH2 Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
    Andere Bezeichnung
    ASAH2 (ASAH2 Produkte)
    Synonyme
    BCDase antikoerper, HNAC1 antikoerper, LCDase antikoerper, N-CDase antikoerper, NCDase antikoerper, AI585898 antikoerper, N-acylsphingosine amidohydrolase 2 antikoerper, ASAH2 antikoerper, Asah2 antikoerper
    Hintergrund

    Synonyms: Acylsphingosine deacylase 2, ASAH2, ASAH2_HUMAN, BCDase, hCD, HNAC1, LCDase, MGC129777, mitochondrial ceramidase, N acylsphingosine amidohydrolase non lysosomal ceramidase 2, N acylsphingosine amidohydrolase 2, N CDase, N-acylsphingosine amidohydrolase 2, N-CDase, NCDase, Neutral ceramidase soluble form, Non lysosomal ceramidase, Non-lysosomal ceramidase.

    Background: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

    Gen-ID
    2298
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