FCGR2B Antikörper (pTyr292)
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- Target Alle FCGR2B Antikörper anzeigen
- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
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Bindungsspezifität
- pTyr292
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Reaktivität
- Human, Maus, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FCGR2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Affe, Maus
- Homologie
- Rat,Dog,Sheep,Pig,Rabbit,Guinea Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human CD32B around the phosphorylation site of Tyr292.
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
- Andere Bezeichnung
- CD32B (FCGR2B Produkte)
- Synonyme
- CD32 antikoerper, CD32B antikoerper, FCG2 antikoerper, FCGR2 antikoerper, IGFR2 antikoerper, FCGR2B antikoerper, AI528646 antikoerper, F630109E10Rik antikoerper, Fc[g]RII antikoerper, FcgRII antikoerper, Fcgr2 antikoerper, Fcgr2a antikoerper, Fcr-2 antikoerper, Fcr-3 antikoerper, Ly-17 antikoerper, Ly-m20 antikoerper, LyM-1 antikoerper, Lym-1 antikoerper, FCRII antikoerper, FcRII antikoerper, Fc fragment of IgG receptor IIb antikoerper, Fc fragment of IgG, low affinity IIb, receptor (CD32) antikoerper, Fc receptor, IgG, low affinity IIb antikoerper, low affinity immunoglobulin gamma Fc region receptor II antikoerper, FCGR2B antikoerper, Fcgr2b antikoerper, LOC100856270 antikoerper
- Hintergrund
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Synonyms: CD32, FCG2, CD32B, FCGR2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, FCGR2B
Background: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
- Gen-ID
- 2213
- UniProt
- P31994
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling
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