FGFRL1 Antikörper (AA 231-330) (Biotin)

Produktnummer ABIN761683

Produktdetails anti-FGFRL1 Antikörper (Biotin)

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Bindungsspezifität: AA 231-330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFRL1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FGFR5/FGFRL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FGFRL1

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Andere Bezeichnung: FGFR5 (FGFRL1 Produkte)

Synonyme: fgfrl1 antikoerper, zgc:64084 antikoerper, FGFR5 antikoerper, FGFR5beta antikoerper, FGFR5gamma antikoerper, Fgfr5 antikoerper, FHFR antikoerper, XFGFRL1 antikoerper, Xndk antikoerper, fgfrl1-a antikoerper, fgfrl1-b antikoerper, ndk antikoerper, im:7154242 antikoerper, fibroblast growth factor receptor like 1a antikoerper, fibroblast growth factor receptor-like 1 antikoerper, fibroblast growth factor receptor like 1 antikoerper, fibroblast growth factor receptor like 1 L homeolog antikoerper, fibroblast growth factor receptor like 1b antikoerper, fgfrl1a antikoerper, Fgfrl1 antikoerper, FGFRL1 antikoerper, fgfrl1.L antikoerper, fgfrl1b antikoerper

Hintergrund:

Synonyms: FGF homologous factor receptor, FGF receptor like protein 1, FGFR 5, FGFR like protein, FGFR5, FGFRL1, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor like 1, FGRL1_HUMAN.

Background: FGFRL1 is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between FGFRL1 and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found.

Gen-ID: 53834

Pathways: RTK Signalweg