Nicastrin Antikörper (AA 21-120) (Biotin)
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- Target Alle Nicastrin (NCSTN) Antikörper anzeigen
- Nicastrin (NCSTN)
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Nicastrin Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Cow,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Nicastrin
- Isotyp
- IgG
- Top Product
- Discover our top product NCSTN Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- Nicastrin (NCSTN)
- Andere Bezeichnung
- Nicastrin (NCSTN Produkte)
- Synonyme
- CG7012 antikoerper, Dmel\\CG7012 antikoerper, Nct antikoerper, Nic antikoerper, S5A antikoerper, ST96B antikoerper, agro antikoerper, dNct antikoerper, nic antikoerper, NCSTN antikoerper, DKFZp469O2418 antikoerper, APH2 antikoerper, 9430068N19Rik antikoerper, AA727311 antikoerper, Aph2 antikoerper, D1Dau13e antikoerper, Kiaa0253 antikoerper, mKIAA0253 antikoerper, nicastrin antikoerper, Nicastrin antikoerper, NCSTN antikoerper, nct antikoerper, ncstn antikoerper, CpipJ_CPIJ001617 antikoerper, Ncstn antikoerper, aph-2 antikoerper
- Hintergrund
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Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
- Gen-ID
- 23385
- UniProt
- Q92542
- Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
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