RND3 Antikörper (AA 51-150)

Produktnummer ABIN762356

Produktdetails anti-RND3 Antikörper

Target: RND3 (rho Family GTPase 3 (RND3))

Bindungsspezifität: AA 51-150

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RND3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RND3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Andere Bezeichnung: Rnd3 (RND3 Produkte)

Synonyme: ARHE antikoerper, Rho8 antikoerper, RhoE antikoerper, memB antikoerper, MGC83857 antikoerper, 2610017M01Rik antikoerper, AI661404 antikoerper, Arhe antikoerper, Rhoe antikoerper, RHOE antikoerper, arhe antikoerper, id:ibd2712 antikoerper, id:ibd2919 antikoerper, rho8 antikoerper, rnd3 antikoerper, wu:fc39h07 antikoerper, zgc:73080 antikoerper, wu:fd06e12 antikoerper, zgc:92324 antikoerper, Rho family GTPase 3 antikoerper, Rho family GTPase 3 L homeolog antikoerper, Rho family GTPase 3a antikoerper, Rho family GTPase 3b antikoerper, RND3 antikoerper, rnd3.L antikoerper, Rnd3 antikoerper, rnd3a antikoerper, rnd3b antikoerper

Hintergrund:

Synonyms: ARHE, memB, Rho family GTPase 3, Rho8, RhoE, RND3_HUMAN.

Background: The Rho family of proteins mediates cytoskeleton organization and cell motility responses. This family contains twenty different members divided into five groups, the Rho-like, Rac-like, Cdc42-like, Rnd and RhoBTB subfamilies. Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form. In their active form they interact with downstream proteins. However, the Rnd subfamily of proteins containing the Rnd1, Rnd2 and RhoE(Rnd3), binds GTP but not GDP and has no GTPase activity. While Rho proteins are required for stress fibre formation in cultured fibroblasts, epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i.e. decrease in stress fibre). Thus, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins.

Gen-ID: 390