Retinoblastoma Binding Protein 4 Antikörper (AA 231-330)

Produktnummer ABIN762866

Produktdetails anti-Retinoblastoma Binding Protein 4 Antikörper

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Bindungsspezifität: AA 231-330

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoblastoma Binding Protein 4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RbAp48

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Retinoblastoma Binding Protein 4

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Andere Bezeichnung: Rbap48 (RBBP4 Produkte)

Synonyme: NURF55 antikoerper, RBAP48 antikoerper, 154659_at antikoerper, 55 antikoerper, CAF-1 antikoerper, CAF1 antikoerper, CAF1-55 antikoerper, CAF1p55 antikoerper, CG4236 antikoerper, Caf-1 antikoerper, Caf1/p55 antikoerper, Caf1p55 antikoerper, Dmel\\CG4236 antikoerper, MSI1/RbAp48/CAC3/LIN-53 antikoerper, NURF antikoerper, NURF-55 antikoerper, Nurf antikoerper, Nurf 55 antikoerper, Nurf-55 antikoerper, Nurf55 antikoerper, P55 antikoerper, RbAp48 antikoerper, S(ls)3 antikoerper, caf-1 antikoerper, caf1 antikoerper, caf1 p55 antikoerper, d-CAF1 antikoerper, dCAF-1 antikoerper, dCAF-1 p55 antikoerper, dNURF antikoerper, p55 antikoerper, p55 CAF1 antikoerper, p55/NURF-55 antikoerper, p55CAF1 antikoerper, nurf55 antikoerper, rbap48 antikoerper, xrbbp4 antikoerper, mRbAp48 antikoerper, RBBP4 antikoerper, rbb4-2 antikoerper, zgc:55349 antikoerper, zgc:77854 antikoerper, wu:fb33a09 antikoerper, wu:fb40e10 antikoerper, RBBP-4 antikoerper, rbbp4 antikoerper, M4E13.110 antikoerper, M4E13_110 antikoerper, MULTICOPY SUPPRESSOR OF IRA1 3 antikoerper, NFC3 antikoerper, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP C 3 antikoerper, RB binding protein 4, chromatin remodeling factor antikoerper, Chromatin assembly factor 1, p55 subunit antikoerper, retinoblastoma binding protein 4 antikoerper, retinoblastoma binding protein 4, chromatin remodeling factor antikoerper, retinoblastoma binding protein 4 L homeolog antikoerper, Transducin family protein / WD-40 repeat family protein antikoerper, retinoblastoma binding protein 4 S homeolog antikoerper, RBBP4 antikoerper, Caf1-55 antikoerper, rbbp4 antikoerper, Rbbp4 antikoerper, rbbp4.L antikoerper, MSI3 antikoerper, rbbp4.S antikoerper

Hintergrund:

Synonyms: RBBP4_HUMAN, Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48.

Background: RbAp48 (Retinoblastoma-binding protein p48 or Rb-associated protein p48)is a WD repeat protein that is a core histone binding subunit common to several complexes involved in chromatin assembly, chromatin remodeling, and histone deacetylation. These complexes include Chromatin Assembly Factor 1 (CAF1), which is required for chromatin assembly following DNA replication and repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and subsequent transcriptional repression, the nucleosome remodeling and histone deacetylation complex NuRD, the nucleosome remodeling factor (NURF) complex, and the PRC2 complex, which promotes repression of homeotic genes during development. RpAp48 also interacts with the retinoblastoma protein, and with SPEN/MINT and BRCA1. It is also a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells.

Gen-ID: 5928

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus