p53 Antikörper
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- Target Alle p53 (TP53) Antikörper anzeigen
- p53 (TP53) (Tumor Protein P53 (TP53))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser p53 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- Nucleus
- Aufreinigung
- Protein G-Sepharose affinity purified.
- Immunogen
- Recombinant fragment of Human TP53 (C-terminus).
- Isotyp
- IgG
- Top Product
- Discover our top product TP53 Primärantikörper
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- Applikationshinweise
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000 .
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 50µg/50µl
- Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Andere Bezeichnung
- TP53 (TP53 Produkte)
- Hintergrund
- This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.
- Molekulargewicht
- 50kDa
- NCBI Accession
- NM_000546
- Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
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