HCV NS5 Antikörper (N-Term)
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- Target Alle HCV NS5 Produkte
- HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
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Bindungsspezifität
- AA 1-19, N-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HCV NS5 Antikörper ist unkonjugiert
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Applikation
- Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Functional Studies (Func)
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- Recombinant Hepatitis C Virus nonstructural protein 5B (NS5B) RNAdependent RNA polymerase (RdRp)
- Klon
- 8B2
- Isotyp
- IgG2a
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS pH 7.4, with 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Upon receipt, store (in aliquots) at -20 to -70 °C.
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Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24089-102, (2008) (PubMed).
: "
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Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24089-102, (2008) (PubMed).
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- Target
- HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
- Andere Bezeichnung
- HCV NS5 (HCV NS5 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
- Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.Synonyms: Hepatitis C Virus, RNA-directed RNA polymerase NS5B
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