RND3 Antikörper (AA 1-245)

Produktnummer ABIN782334

Produktdetails anti-RND3 Antikörper

Target: RND3 (rho Family GTPase 3 (RND3))

Bindungsspezifität: AA 1-245

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RND3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: Recognizes RND3 / ARHE.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography

Immunogen: RND3 antibody was raised against RND3 (AAH12513, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.

Klon: 1D2

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C or -80 °C.

Details zu RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Andere Bezeichnung: RND3 / ARHE (RND3 Produkte)

Synonyme: ARHE antikoerper, Rho8 antikoerper, RhoE antikoerper, memB antikoerper, MGC83857 antikoerper, 2610017M01Rik antikoerper, AI661404 antikoerper, Arhe antikoerper, Rhoe antikoerper, RHOE antikoerper, arhe antikoerper, id:ibd2712 antikoerper, id:ibd2919 antikoerper, rho8 antikoerper, rnd3 antikoerper, wu:fc39h07 antikoerper, zgc:73080 antikoerper, wu:fd06e12 antikoerper, zgc:92324 antikoerper, Rho family GTPase 3 antikoerper, Rho family GTPase 3 L homeolog antikoerper, Rho family GTPase 3a antikoerper, Rho family GTPase 3b antikoerper, RND3 antikoerper, rnd3.L antikoerper, Rnd3 antikoerper, rnd3a antikoerper, rnd3b antikoerper

Hintergrund: Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE

Gen-ID: 390

NCBI Accession: NP_005159

UniProt: P61587