Filamin A Antikörper (AA 1-839)

Produktnummer ABIN782404

Produktdetails anti-Filamin A Antikörper

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Bindungsspezifität: AA 1-839

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Filamin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to FLNA / FMD.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: FLNA antibody was raised against fLNA (AAH14654, 1 a.a. ~ 839 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 4E10-1B2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C to -80 °C.

Details zu Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Andere Bezeichnung: Filamin-A (FLNA Produkte)

Hintergrund: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking.Synonyms: Actin-binding protein 280, Alpha-filamin, Endothelial actin-binding protein, FLN, FLN1, FLNA, Filamin-1, Non-muscle filamin

Gen-ID: 2316

NCBI Accession: NP_001104026

UniProt: P21333

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location