GSTA1 Antikörper (AA 1-222)

Produktnummer ABIN782405

Produktdetails anti-GSTA1 Antikörper

Target: GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

Bindungsspezifität: AA 1-222

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GSTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to GSTA1.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: GSTA1 antibody was raised against gSTA1 (AAH53578.1, 1 a.a. ~ 222 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 2F7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C to -80 °C.

Details zu GSTA1

Target: GSTA1 (Glutathione S-Transferase alpha 1 (GSTA1))

Andere Bezeichnung: GSTA1 (GSTA1 Produkte)

Synonyme: GST2 antikoerper, GSTA1-1 antikoerper, GTH1 antikoerper, Gst2-1 antikoerper, OTTMUSG00000031890 antikoerper, GSTA3 antikoerper, GST antikoerper, GSTA1 antikoerper, gst2 antikoerper, gth1 antikoerper, gsta1-1 antikoerper, Gsta1 antikoerper, Gst-2 antikoerper, Gst-3 antikoerper, Gst2 antikoerper, Gst3 antikoerper, glutathione S-transferase alpha 1 antikoerper, glutathione S-transferase, alpha 1 (Ya) antikoerper, glutathione S-transferase alpha 3 antikoerper, glutathione S-transferase alpha 5 antikoerper, glutathione S-transferase alpha 1 L homeolog antikoerper, glutathione S-transferase alpha 2 antikoerper, glutathione S-transferase mu 2 (muscle) antikoerper, Glutathione S-transferase 2 antikoerper, glutathione S-transferase A antikoerper, glutathione S-transferase Gst2 antikoerper, glutathione S-transferase 2 antikoerper, GSTA1 antikoerper, Gsta1 antikoerper, GSTA3 antikoerper, GSTA5 antikoerper, gsta1.L antikoerper, gsta1 antikoerper, Gsta2 antikoerper, GSTM2 antikoerper, gst-2 antikoerper, LOC100713029 antikoerper, gst2 antikoerper, LOC101897277 antikoerper

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.Synonyms: GST class-alpha member 1, GST-epsilon, GSTA1-1, GTH1, Glutathione S-transferase A1, HA subunit 1

Gen-ID: 2938

NCBI Accession: NP_665683

UniProt: P08263