OCRL Antikörper (AA 146-240)

Produktnummer ABIN782420

Produktdetails anti-OCRL Antikörper

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Bindungsspezifität: AA 146-240

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser OCRL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to OCRL.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: OCRL antibody was raised against oCRL (NP_000267, 146 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 4A6

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Andere Bezeichnung: OCRL (OCRL Produkte)

Hintergrund: RelevanceConverts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes.Synonyms: INPP5F, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein, OCRL-1, OCRL1

Gen-ID: 4952

NCBI Accession: NP_000267

UniProt: Q01968

Pathways: Inositol Metabolic Process