Aggrecan Antikörper (N-Term)
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- Target Alle Aggrecan (ACAN) Antikörper anzeigen
- Aggrecan (ACAN)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aggrecan Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Immunogen
- Synthetic peptide (- KLH conjugated) corresponding to N-terminal domain of Human Aggrecan.
- Isotyp
- IgG
- Top Product
- Discover our top product ACAN Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- Target
- Aggrecan (ACAN)
- Andere Bezeichnung
- Aggrecan (ACAN Produkte)
- Synonyme
- AGC1 antikoerper, AGCAN antikoerper, CSPG1 antikoerper, CSPGCP antikoerper, MSK16 antikoerper, SEDK antikoerper, Agc antikoerper, Agc1 antikoerper, Cspg1 antikoerper, b2b183Clo antikoerper, cmd antikoerper, aggrecan antikoerper, aggrecan core protein antikoerper, ACAN antikoerper, Acan antikoerper, LOC100380783 antikoerper, AGC antikoerper
- Hintergrund
- Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.Synonyms: ACAN, AGC1, CSPG1, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1, MSK16
- Gen-ID
- 9606
- UniProt
- P16112
- Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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