ESRP2 Antikörper (C-Term)
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- Target Alle ESRP2 Antikörper anzeigen
- ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ESRP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects ESRP2 / RBM35B at C-term. RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist, this antibody will detect all three.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid peptide near the carboxy terminus of human RBM35B
- Top Product
- Discover our top product ESRP2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
- Andere Bezeichnung
- ESRP2 / RBM35B (ESRP2 Produkte)
- Synonyme
- RBM35B antikoerper, 9530027K23Rik antikoerper, Rbm35b antikoerper, RGD1310855 antikoerper, cb404 antikoerper, fa07a06 antikoerper, rbm35b antikoerper, sb:cb404 antikoerper, zgc:77254 antikoerper, epithelial splicing regulatory protein 2 antikoerper, microRNA 6773 antikoerper, ESRP2 antikoerper, Esrp2 antikoerper, MIR6773 antikoerper, esrp2 antikoerper
- Hintergrund
- RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.Synonyms: Epithelial splicing regulatory protein 2, RNA-binding motif protein 35B, RNA-binding protein 35B
- Gen-ID
- 80004
- NCBI Accession
- NP_079215
- UniProt
- Q9H6T0
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