This antibody detects CTNNBL1 at C-term. CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist, this antibody will detect all but isoform b.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse, rat
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
20 amino acid peptide near the carboxy terminus of human CTTNBL1
ctnnbl1 antikoerper, MGC76112 antikoerper, MGC82423 antikoerper, PDGFRA antikoerper, MGC84931 antikoerper, C20orf33 antikoerper, NAP antikoerper, P14L antikoerper, PP8304 antikoerper, dJ633O20.1 antikoerper, 5730471K09Rik antikoerper, NYD-SP19 antikoerper, catenin beta like 1 antikoerper, catenin beta like 1 S homeolog antikoerper, catenin beta like 1 L homeolog antikoerper, catenin, beta like 1 antikoerper, ctnnbl1 antikoerper, CTNNBL1 antikoerper, ctnnbl1.S antikoerper, ctnnbl1.L antikoerper, Ctnnbl1 antikoerper
Hintergrund
The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.Synonyms: Beta-catenin-like protein 1, C20orf33, NYD-SP19, Nuclear-associated protein, Testis development protein NYD-SP19