MYZAP Antikörper (C-Term)

Produktnummer ABIN783419

Produktdetails anti-MYZAP Antikörper

Target: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYZAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects MYOZAP at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of human MYOZAP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu MYZAP

Target: MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

Andere Bezeichnung: MYOZAP (MYZAP Produkte)

Synonyme: AA407270 antikoerper, AV006038 antikoerper, Gcom1 antikoerper, Gm640 antikoerper, Grinl1a7 antikoerper, Myozap antikoerper, Myzap antikoerper, GLURR2 antikoerper, GRINL1B antikoerper, GCOM1 antikoerper, Gup antikoerper, Gup1 antikoerper, Gup2 antikoerper, MYOZAP antikoerper, myocardial zonula adherens protein antikoerper, GRINL1B complex locus 2 (pseudogene) antikoerper, Myzap antikoerper, GCOM2 antikoerper, MYZAP antikoerper

Hintergrund: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein . It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.Synonyms: GCOM1, GRINL1A, Gup, Gup1, Myocardium-enriched zonula occludens-1-interacting protein, glutamate receptor ionotropic N-methyl D-aspartate-like 1A

Gen-ID: 145781

NCBI Accession: NP_001018100

UniProt: P0CAP1