RABGEF1 Antikörper (Center)
-
- Target Alle RABGEF1 Antikörper anzeigen
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
-
Bindungsspezifität
- Center
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RABGEF1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects RABGEF1 at Center. At least four isoforms of RABEX5 are known to exist, this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 19 amino acid peptide near the center terminus of human RABEX5
- Top Product
- Discover our top product RABGEF1 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
-
- Target
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- Andere Bezeichnung
- RABGEF1 (RABGEF1 Produkte)
- Synonyme
- Rab5ef antikoerper, Rabex5 antikoerper, Rin2 antikoerper, RABEX5 antikoerper, rabex-5 antikoerper, rabgef1 antikoerper, RAB guanine nucleotide exchange factor (GEF) 1 antikoerper, RAB guanine nucleotide exchange factor 1 antikoerper, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog antikoerper, Rabgef1 antikoerper, RABGEF1 antikoerper, rabgef1.L antikoerper
- Hintergrund
- RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.Synonyms: RABEX5, RAP1, Rab5 GDP/GTP exchange factor, Rabaptin-5-associated exchange factor for Rab5, Rabex-5
- Gen-ID
- 27342
- NCBI Accession
- NP_055319
- UniProt
- Q9UJ41
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-