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ZNF219 Antikörper (N-Term)

ZNF219 Reaktivität: Human, Ratte, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783427
  • Target Alle ZNF219 Antikörper anzeigen
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 10
    Kaninchen
    Klonalität
    • 10
    Polyklonal
    Konjugat
    • 10
    Dieser ZNF219 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects ZNF219 at N-term. At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the amino terminus of human ZFP219
    Top Product
    Discover our top product ZNF219 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Andere Bezeichnung
    ZNF219 (ZNF219 Produkte)
    Synonyme
    ZNF219 antikoerper, ZFP219 antikoerper, Znf219 antikoerper, 2010302A17Rik antikoerper, zinc finger protein 219 antikoerper, ZNF219 antikoerper, Zfp219 antikoerper
    Hintergrund
    ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.Synonyms: Zinc finger protein 219
    Gen-ID
    51222
    NCBI Accession
    NP_001095142
    UniProt
    Q9P2Y4
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