Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DYRK2 Antikörper (C-Term)

DYRK2 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783436
  • Target Alle DYRK2 Antikörper anzeigen
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 42
    • 32
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 7
    • 1
    Kaninchen
    Klonalität
    • 56
    • 7
    Polyklonal
    Konjugat
    • 26
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DYRK2 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 33
    • 27
    • 13
    • 13
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects DYRK2 at C-term. Two isoforms of DYRK2 are known to exist, this antibody will recognize both isoforms. DYRK2 antibody will not cross-react with other DYRK family members.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the carboxy terminus of human DYRK2
    Top Product
    Discover our top product DYRK2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Andere Bezeichnung
    DYRK2 (DYRK2 Produkte)
    Synonyme
    DYRK2 antikoerper, fc18c09 antikoerper, si:ch211-266a5.8 antikoerper, wu:fa09g03 antikoerper, wu:fc18c09 antikoerper, 1810038L18Rik antikoerper, dual specificity tyrosine phosphorylation regulated kinase 2 antikoerper, dual specificity tyrosine-phosphorylation-regulated kinase 2 antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 antikoerper, DYRK2 antikoerper, CpipJ_CPIJ014802 antikoerper, dyrk2 antikoerper, Dyrk2 antikoerper
    Hintergrund
    DYRK2 is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family that is thought to be involved in cellular proliferation and apoptosis. Under normal conditions, nuclear but not cytoplasmic DYRK2 is ubiquitinated by MDM2, leading to its constitutive degradation. However, upon exposure to genotoxic stress, ATM phosphorylates DYRK2, leading to its dissociation from MDM2 and its phosphorylation of p53, thereby inducing apoptosis. Recent evidence also suggests that DYRK2 may serve as a scaffold that facilitates assembly of an E3 ubiquitin ligase.Synonyms: Dual specificity tyrosine-phosphorylation-regulated kinase 2
    Gen-ID
    8445
    NCBI Accession
    NP_003574
    UniProt
    Q92630
    Pathways
    Regulation of Carbohydrate Metabolic Process
Sie sind hier:
Kundenservice