This antibody detects TYW3 at Center. TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.
Kreuzreaktivität (Details)
Species reactivity (tested):Human, mouse
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
17 amino acid peptide near the center of human TYW3
C1orf171 antikoerper, 5230400J09Rik antikoerper, tRNA-yW synthesizing protein 3 homolog L homeolog antikoerper, tRNA-yW synthesizing protein 3 homolog antikoerper, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) antikoerper, tyw3.L antikoerper, TYW3 antikoerper, Tyw3 antikoerper
Hintergrund
TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.Synonyms: C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3