Der Kaninchen Polyklonal Anti-AP3M1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, AP3M1 in Proben von Human, Maus und Ratte zu detektieren.
AP3M1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
PE
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS containing 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target
AP3M1
(Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))
Andere Bezeichnung
AP3 Complex Subunit mu-1
Hintergrund
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.Synonyms: AP-3 adapter complex mu3A subunit, AP3M1, Adapter-related protein complex 3 mu-1 subunit, Mu-adaptin 3A, Mu3A-adaptin