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TMEM88 Antikörper (C-Term)

TMEM88 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783510
  • Target Alle TMEM88 Produkte
    TMEM88 (Transmembrane Protein 88 (TMEM88))
    Bindungsspezifität
    • 4
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 5
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Konjugat
    • 2
    • 1
    • 1
    • 1
    Dieser TMEM88 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects TMEM88 / TMEM88A at C-term.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    19 amino acid peptide near the carboxy terminus of human TMEM88
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    TMEM88 (Transmembrane Protein 88 (TMEM88))
    Abstract
    TMEM88 Produkte
    Synonyme
    2600017H02Rik antikoerper, RGD1561781 antikoerper, zgc:77242 antikoerper, transmembrane protein 88 antikoerper, transmembrane protein 88B antikoerper, transmembrane protein 88 a antikoerper, Tmem88 antikoerper, TMEM88 antikoerper, TMEM88B antikoerper, tmem88 antikoerper, tmem88a antikoerper
    Hintergrund
    Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.Synonyms: Transmembrane protein 88
    Gen-ID
    92162
    NCBI Accession
    NP_981956
    UniProt
    Q6PEY1
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