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CMYA5 Antikörper (C-Term)

CMYA5 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783522
  • Target Alle CMYA5 Produkte
    CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
    Bindungsspezifität
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser CMYA5 Antikörper ist unkonjugiert
    Applikation
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Myospryn at C-term. SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the carboxy terminus of human SPRYD2
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
    Andere Bezeichnung
    Myospryn (CMYA5 Produkte)
    Synonyme
    cmya5l antikoerper, DKFZp469P2126 antikoerper, C5orf10 antikoerper, SPRYD2 antikoerper, TRIM76 antikoerper, 2310076E16Rik antikoerper, 2310076E21Rik antikoerper, AA420382 antikoerper, AI504003 antikoerper, Srfsd antikoerper, Tims antikoerper, sr553 antikoerper, cardiomyopathy associated 5 antikoerper, CMYA5 antikoerper, cmya5 antikoerper, Cmya5 antikoerper
    Hintergrund
    SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.Synonyms: C5orf10, CMYA5, Cardiomyopathy-associated protein 5, DTNBP2, Dystrobrevin-binding protein 2, Genethonin-3, SPRY domain-containing protein 2, SPRYD2, TRIM76, Tripartite motif-containing protein 76
    Gen-ID
    202333
    NCBI Accession
    NP_705838
    UniProt
    Q8N3K9
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