FREM2 Antikörper (Center)

Produktnummer ABIN783636

Produktdetails anti-FREM2 Antikörper

Target: FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))

Bindungsspezifität: Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FREM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts with Human and Mouse FREM2 and is predicted to not cross-react with other FRAS members. This antibody recognizes both isoforms of FREM2.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the center of Human FREM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FREM2

Target: FREM2 (Fras1 Related Extracellular Matrix Protein 2 (FREM2))

Andere Bezeichnung: FREM2 (FREM2 Produkte)

Synonyme: 6030440P17Rik antikoerper, 8430406N05Rik antikoerper, Gm409 antikoerper, b2b1562Clo antikoerper, my antikoerper, ne antikoerper, nv1 antikoerper, RGD1566012 antikoerper, FRAS1 related extracellular matrix protein 2 antikoerper, Fras1 related extracellular matrix protein 2 antikoerper, FREM2 antikoerper, Frem2 antikoerper

Hintergrund: FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.Synonyms: ECM3 homolog, FRAS1-related extracellular matrix protein 2

Gen-ID: 341640

NCBI Accession: NP_997244

UniProt: Q5SZK8