TCTN3 Antikörper (C-Term)

Produktnummer ABIN783639

Produktdetails anti-TCTN3 Antikörper

Target: TCTN3 (Tectonic Family Member 3 (TCTN3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCTN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human TCTN3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu TCTN3

Target: TCTN3 (Tectonic Family Member 3 (TCTN3))

Andere Bezeichnung: Tectonic-3 (TCTN3 Produkte)

Synonyme: RGD1305166 antikoerper, C10orf61 antikoerper, JBTS18 antikoerper, OFD4 antikoerper, TECT3 antikoerper, 4930521E07Rik antikoerper, AI197391 antikoerper, Tect3 antikoerper, tectonic family member 3 antikoerper, Tctn3 antikoerper, TCTN3 antikoerper

Hintergrund: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58 % similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.Synonyms: C10orf61, TCTN3, TECT3

Gen-ID: 26123

NCBI Accession: NP_056446

UniProt: Q6NUS6