SCUBE1 Antikörper (Center)

Produktnummer ABIN783649

Produktdetails anti-SCUBE1 Antikörper

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCUBE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human SCUBE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: 14 amino acid peptide near the center of human SCUBE1

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SCUBE1

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Andere Bezeichnung: SCUBE1 (SCUBE1 Produkte)

Synonyme: 7330410C13Rik antikoerper, A630023E24Rik antikoerper, signal peptide, CUB domain and EGF like domain containing 1 antikoerper, signal peptide, CUB domain, EGF-like 1 antikoerper, SCUBE1 antikoerper, Scube1 antikoerper

Hintergrund: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1

Gen-ID: 80274

NCBI Accession: NP_766638

UniProt: Q8IWY4