NALP8 Antikörper (N-Term)

Produktnummer ABIN783713

Der Kaninchen Polyklonal Anti-NALP8-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, NALP8 in Proben von Human zu detektieren.

Kurzübersicht für NALP8 Antikörper (N-Term) (ABIN783713)

Target: NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NALP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-NALP8 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects NALP8 at N-term. This antibody is predicted to not cross-react with other NALP family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of Human NALP8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NALP8

Target: NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))

Andere Bezeichnung: NALP8

Hintergrund: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.Synonyms: LRR and PYD domains-containing protein 8, NACHT, NLRP8, NOD16, PAN4, PYRIN and NACHT-containing protein 4

Gen-ID: 126205

NCBI Accession: NP_789781

UniProt: Q86W28

Pathways: Inflammasome