NLRP11 Antikörper (C-Term)

Produktnummer ABIN783717

Produktdetails anti-NLRP11 Antikörper

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody will recognize all three isoforms of NALP2 and is predicted to not cross-react with other NALP family members.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Affinity Chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of Human NALP11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NLRP11

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Andere Bezeichnung: NALP11 (NLRP11 Produkte)

Synonyme: CLR19.6 antikoerper, NALP11 antikoerper, NOD17 antikoerper, PAN10 antikoerper, PYPAF6 antikoerper, PYPAF7 antikoerper, NLR family pyrin domain containing 11 antikoerper, NLRP11 antikoerper

Hintergrund: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.Synonyms: LRR and PYD domains-containing protein 11, NACHT, NLRP11, NOD17, Nucleotide-binding oligomerization domain protein 17, PYPAF6, PYRIN-containing APAF1-like protein 6

Gen-ID: 204801

NCBI Accession: NP_659444

UniProt: P59045

Pathways: Inflammasome