RGS17 Antikörper (AA 148-160)

Produktnummer ABIN784001

Produktdetails anti-RGS17 Antikörper

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Bindungsspezifität: AA 148-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: Recognizes RGS17.
Cellular Localization: Membrane, Lipid-anchor, Nucleus, Cytoplasm.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Antigen-Affinity Chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 148 and 160 of Human RGS17.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C.

Details zu RGS17

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Andere Bezeichnung: RGS17 (RGS17 Produkte)

Hintergrund: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: RGS-17, RGSZ2, Regulator of G-protein signaling 17

Gen-ID: 26575, 9606

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling