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PDGFRA Antikörper (AA 1035-1053)
PDGFRA
Reaktivität: Human, Maus, Ratte, Huhn, Xenopus laevis
WB, IHC (p), IP
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-PDGFRA Antikörper
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Target
Alle PDGFRA Antikörper anzeigen
PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Bindungsspezifität
Alle Epitope für PDGFRA Antikörper
AA 1035-1053
Reaktivität
Alle Reaktivitäten für PDGFRA Antikörper
Human, Maus, Ratte, Huhn, Xenopus laevis
Wirt
Alle Wirte für PDGFRA Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PDGFRA Antikörper
Polyklonal
Konjugat
Alle Konjugate für PDGFRA Antikörper
Dieser PDGFRA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PDGFRA Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Sequenz
C-GKRNRHSSQT SEESAIETG Remarks: Antigen Modificati on: Amino acids 1035-1053
Spezifität
Recognizes Human PDGF Receptor Type A, doublet, Mr 150/170 kDa.
Kreuzreaktivität (Details)
Species reactivity (expected):Chicken, Frog, Mouse, Rat, Zebrafish. Species reactivity (tested):Human.
Aufreinigung
Immunoaffinity Chromatography
Immunogen
Synthetic peptide KLH-conjugated corresponding to amino acids 1035-1053 of Human PDGF.
Isotyp
IgG
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Discover our top product PDGFRA Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
0.2 M Tris-Glycine, pH 7.4 containing 0.12 M Sodium Chloride and 0.05 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
Details zu PDGFRA
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Target
PDGFRA
(Platelet Derived Growth Factor Receptor alpha (PDGFRA))
Andere Bezeichnung
CD140a / PDGFRA (PDGFRA Produkte )
Synonyme
AI115593 antikoerper, CD140a antikoerper, Pdgfr-2 antikoerper, APDGFR antikoerper, PDGFACE antikoerper, CD140A antikoerper, PDGFR-2 antikoerper, PDGFR2 antikoerper, RHEPDGFRA antikoerper, PDGFR antikoerper, PDGFR-A antikoerper, platelet derived growth factor receptor alpha antikoerper, platelet derived growth factor receptor, alpha polypeptide antikoerper, platelet-derived growth factor receptor, alpha polypeptide L homeolog antikoerper, platelet-derived growth factor receptor, alpha polypeptide antikoerper, PDGFRA antikoerper, Pdgfra antikoerper, pdgfra.L antikoerper
Hintergrund
Platelet-derived Growth Factor Receptor Alpha (PDGFR alpha), a member of the a PDGF Receptor tyrosine kinase family, is a mediator of the biological actions of platelet-derived growth factor (PDGF). PDGF binding to PDGF receptors result in stimulation of cell growth, chemotaxis, and cell shape changes. Unlike PDGFR beta, PDGFR alpha can bind to both PDGF subunits. PDGFR alpha has been implicated in the development of spina bifida. In various mouse models, deregulated PDGFR alpha expression was found to result in congenital neural tube defects. In humans, various PDGFRA promoter haplotypes have been associated with neural tube defects.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
Gen-ID
5156
NCBI Accession
NP_006197
Pathways
RTK Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Platelet-derived growth Factor Receptor Signaling
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