PMVK Antikörper (AA 15-120) (Biotin)

Produktnummer ABIN801080

Produktdetails anti-PMVK Antikörper (Biotin)

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Bindungsspezifität: AA 15-120

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMVK Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PMVK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PMVK

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Andere Bezeichnung: PMVK (PMVK Produkte)

Synonyme: MPK_Bm antikoerper, F5M6.9 antikoerper, F5M6_9 antikoerper, zgc:162701 antikoerper, HUMPMKI antikoerper, PMK antikoerper, PMKA antikoerper, PMKASE antikoerper, 1110011E12Rik antikoerper, 2900002L22Rik antikoerper, AV001327 antikoerper, phosphomevalonate kinase antikoerper, GHMP kinase family protein antikoerper, PMVK antikoerper, Mpk antikoerper, AT1G31910 antikoerper, CpipJ_CPIJ015413 antikoerper, Bm1_05275 antikoerper, pmvk antikoerper, LOAG_11811 antikoerper, Tsp_06629 antikoerper, LOC100282968 antikoerper, Pmvk antikoerper

Hintergrund:

Synonyms: PMK, PMKA, PMKASE, HUMPMKI, Phosphomevalonate kinase, hPMK, PMVK, PMKI

Background: PMVK is a 192 amino acid peroxisomal enzyme belonging to the nucleoside monophosphate (NMP) kinase family and is expressed in heart, liver, skeletal muscle, kidney, and pancreas with lower expression in brain, placenta and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. PMVK exists as a monomer and is encoded by a gene located on human chromosome 1, which houses over 3,000 genes and is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome.

Gen-ID: 10654

UniProt: Q15126