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IRS2 Antikörper (pSer731)

IRS2 Reaktivität: Human, Maus, Ratte FACS, IF (cc) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN801468
  • Target Alle IRS2 Antikörper anzeigen
    IRS2 (Insulin Receptor Substrate 2 (IRS2))
    Bindungsspezifität
    • 16
    • 16
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer731
    Reaktivität
    • 76
    • 43
    • 29
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 77
    Kaninchen
    Klonalität
    • 77
    Polyklonal
    Konjugat
    • 22
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRS2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 36
    • 30
    • 27
    • 18
    • 10
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human IRS-2 around the phosphorylation site of Ser731
    Isotyp
    IgG
    Top Product
    Discover our top product IRS2 Primärantikörper
  • Applikationshinweise
    WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    IRS2 (Insulin Receptor Substrate 2 (IRS2))
    Andere Bezeichnung
    Irs-2 (IRS2 Produkte)
    Synonyme
    IRS2 antikoerper, si:dkeyp-24d6.1 antikoerper, IRS-2 antikoerper, 4PS antikoerper, Irs-2 antikoerper, insulin receptor substrate 2 antikoerper, insulin receptor substrate 2a antikoerper, insulin receptor substrate 2b antikoerper, IRS2 antikoerper, irs2a antikoerper, irs2b antikoerper, Irs2 antikoerper
    Hintergrund

    Synonyms: Insulin Receptor Substrate 2, IRS 2, IRS2.

    Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

    Gen-ID
    8660
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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