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DUX4 Antikörper (C-Term)

DUX4 Reaktivität: Human WB, IHC, IF, ICC Wirt: Maus Monoclonal P2B1 unconjugated
Produktnummer ABIN863109
  • Target Alle DUX4 Antikörper anzeigen
    DUX4 (Double Homeobox 4 (DUX4))
    Bindungsspezifität
    • 26
    • 15
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 78
    • 8
    • 8
    • 1
    • 1
    Human
    Wirt
    • 60
    • 18
    Maus
    Klonalität
    • 60
    • 16
    Monoklonal
    Konjugat
    • 18
    • 8
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUX4 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 32
    • 19
    • 16
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~45 kDa. No cross-reactivity with DUX4c.
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Protein G Purified
    Immunogen
    C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
    Klon
    P2B1
    Isotyp
    IgG1
    Top Product
    Discover our top product DUX4 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN863109 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    DUX4 (Double Homeobox 4 (DUX4))
    Andere Bezeichnung
    DUX4 (DUX4 Produkte)
    Synonyme
    DUX4 antikoerper, DUX4L antikoerper, double homeobox, 4 antikoerper, double homeobox 4 antikoerper, DUX4 antikoerper
    Hintergrund
    DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
    Gen-ID
    22947
    NCBI Accession
    NP_149418
    UniProt
    F5GZ66
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