Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SLC9A3 Antikörper

SLC9A3 Reaktivität: Ratte WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN863199
  • Target Alle SLC9A3 Antikörper anzeigen
    SLC9A3 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3))
    Reaktivität
    • 41
    • 39
    • 16
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    Ratte
    Wirt
    • 56
    • 4
    Kaninchen
    Klonalität
    • 56
    • 4
    Polyklonal
    Konjugat
    • 19
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLC9A3 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 15
    • 14
    • 13
    • 13
    • 13
    • 12
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    Most abundant in colon and small intestine, followed by kidney and stomach. In kidney, expressed in proximal tubules and outer medulla (at protein level),Detects ~84 kDa.
    Kreuzreaktivität
    Maus, Ratte
    Aufreinigung
    Protein A Purified
    Immunogen
    Synthetic peptide mapping to AA 809 to 831 of rat sequence
    Top Product
    Discover our top product SLC9A3 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • IHC (1:25)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN863199 was sufficient for detection of HNE3 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Jones, Bailey, Murray, Lu, McNeilly, Schlötzer-Schrehardt, Lennon, Sado, Brownstein, Mullins, Kadler, Van Agtmael: "ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice." in: Disease models & mechanisms, Vol. 9, Issue 2, pp. 165-76, (2016) (PubMed).

    Lee, Osis, Handlogten, Guo, Verlander, Weiner: "Effect of dietary protein restriction on renal ammonia metabolism." in: American journal of physiology. Renal physiology, Vol. 308, Issue 12, pp. F1463-73, (2015) (PubMed).

    Bourgeois, Bounoure, Christensen, Ramakrishnan, Houillier, Devuyst, Wagner: "Haploinsufficiency of the ammonia transporter Rhcg predisposes to chronic acidosis: Rhcg is critical for apical and basolateral ammonia transport in the mouse collecting duct." in: The Journal of biological chemistry, Vol. 288, Issue 8, pp. 5518-29, (2013) (PubMed).

  • Target
    SLC9A3 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3))
    Andere Bezeichnung
    NHE3 (SLC9A3 Produkte)
    Synonyme
    SLC9A3 antikoerper, 9030624O13Rik antikoerper, AI930210 antikoerper, NHE-3 antikoerper, NHE3 antikoerper, Nhe3 antikoerper, solute carrier family 9 member A3 antikoerper, sodium/hydrogen exchanger 3 antikoerper, Sodium/hydrogen exchanger 3 antikoerper, putative sodium/hydrogen exchanger 3 (nhe3) antikoerper, solute carrier family 9 (sodium/hydrogen exchanger), member 3 antikoerper, SLC9A3 antikoerper, LOC5570922 antikoerper, GL50803_102647 antikoerper, Smp_045680 antikoerper, Slc9a3 antikoerper
    Hintergrund
    Sodium-hydrogen exchanger 3 (NHE3, Slc9a3) is an epithelial transport protein that carries out 1:1 exchange of Na+ and H+ across the plasma membrane. It is apically located in the proximal tubule of the kidney, the thick ascending limb of the kidney, and in small intestine (1). NHE3 is phosphorylated and regulated by multiple kinases including PKA, SGK1 and CK2. It can be phosphorylated by calyculin A, and dephosphorylated by PP1 catalytic subunit in vitro (2).
    Gen-ID
    24784
    NCBI Accession
    NP_036786
    UniProt
    P26433
    Pathways
    Proton Transport
Sie sind hier:
Kundenservice