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p53 Antikörper

TP53 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN866051

Datenblatt (PDF)

Target Alle p53 (TP53) Antikörper anzeigen

p53 (TP53) (Tumor Protein P53 (TP53))
Reaktivität
835

255

211

107

50

34

33

19

10

9

7

6

6

3

3

3

3

2

2

2

2

1

1

1
Human
Wirt
623

229

6

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
559

301

1
Polyklonal
Konjugat
485

38

32

19

19

13

13

13

13

13

13

13

13

13

12

12

11

11

11

11

11

11

11

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser p53 Antikörper ist unkonjugiert
Applikation
668

298

250

202

200

149

128

124

119

68

59

35

18

16

13

12

9

9

8

6

4

3

3

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB)

Spezifität

This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of p53.

Kreuzreaktivität

Human, Maus

Produktmerkmale

Positive Control: A431. Cellular Localization: Cytoplasm, nucleus

Aufreinigung

Immunogen affinity purified

Isotyp

IgG

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anti-Tumor Protein P53 (TP53) (AA 1-100) antibody
TP53 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

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anti-Tumor Protein P53 (TP53) (AA 293-322) antibody
TP53 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7777 unconjugated

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TP53 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 Reaktivität: Human WB, ELISA, IF, IHC (p), IP Wirt: Maus Monoclonal 2C3 unconjugated

anti-Tumor Protein P53 (TP53) (AA 94-201) antibody
TP53 Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2C11 unconjugated

anti-Tumor Protein P53 (TP53) (acLys319) antibody
TP53 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:500-1,000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5mg/ml

Buffer

1xTBS (pH7.4), 0.5% BSA, 25% Glycerol

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Andere Bezeichnung

p53 (TP53 Produkte)

Hintergrund

P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. P53 is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is frequently mutated or inactivated in about 60% of cancers

Molekulargewicht

~70kDa

UniProt

Q91XH8

Pathways

p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt