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c-MYC Antikörper (C-Term)
MYC
Reaktivität: Human
WB
Wirt: Maus
Monoclonal
unconjugated
Produktdetails anti-c-MYC Antikörper
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Target
Alle c-MYC (MYC) Antikörper anzeigen
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Bindungsspezifität
Alle Epitope für c-MYC Antikörper
AA 410-432, C-Term
Reaktivität
Alle Reaktivitäten für c-MYC Antikörper
Human
Wirt
Alle Wirte für c-MYC Antikörper
Maus
Klonalität
Alle Klonalitäten für c-MYC Antikörper
Monoklonal
Konjugat
Alle Konjugate für c-MYC Antikörper
Dieser c-MYC Antikörper ist unkonjugiert
Applikation
Alle Applikationen für c-MYC Antikörper
Western Blotting (WB)
Spezifität
This mouse mAb only detects transfected proteins.
Aufreinigung
Affinity purified
Immunogen
Peptide sequence derived from C-terminal (AA 410-432) of human c-Myc conjugated with KLH.
Top Product
Discover our top product MYC Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Western blotting: 1:500-1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use. Store at -20 °C for long term preservation. Avoid freezing and thawing repeatly.
Referenzen für anti-c-MYC Antikörper (ABIN871631)
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Yang, Xia, Hawke, Li, Liang, Xing, Aldape, Hunter, Alfred Yung, Lu : "PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. " in: Cell , Vol. 150 , Issue 4 , pp. 685-96 , (2012 ) (PubMed ).
Yang, Zheng, Xia, Ji, Chen, Guo, Lyssiotis, Aldape, Cantley, Lu : "ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. " in: Nature cell biology , Vol. 14 , Issue 12 , pp. 1295-304 , (2012 ) (PubMed ).
Details zu c-MYC
(ausblenden)
Target
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Andere Bezeichnung
Myc Proto-Oncogene protein (MYC Produkte )
Synonyme
MRTL antikoerper, MYCC antikoerper, bHLHe39 antikoerper, c-Myc antikoerper, CMYC antikoerper, c-myc antikoerper, C-MYC antikoerper, LOC100136746 antikoerper, ARC antikoerper, B430311C09Rik antikoerper, MYC antikoerper, NOP antikoerper, Nop30 antikoerper, RNCMYC antikoerper, mMyc antikoerper, AU016757 antikoerper, Myc2 antikoerper, Niard antikoerper, Nird antikoerper, cmyc antikoerper, zc-myc antikoerper, c-myc II antikoerper, myc-B antikoerper, myc2 antikoerper, myc1 antikoerper, CMyc antikoerper, zgc:55680 antikoerper, CG10798 antikoerper, D-Myc antikoerper, DM antikoerper, DMYc antikoerper, Dm antikoerper, Dmel\CG10798 antikoerper, Dmyc antikoerper, EG:BACN5I9.1 antikoerper, anon-WO03040301.171 antikoerper, bHLHe57 antikoerper, c-MYC antikoerper, d-myc antikoerper, dMYC antikoerper, dMyc antikoerper, dMyc1 antikoerper, da antikoerper, dm antikoerper, dm/dMyc antikoerper, dm/myc antikoerper, dmyc antikoerper, dmyc1 antikoerper, l(1)G0139 antikoerper, l(1)G0354 antikoerper, l(1)G0359 antikoerper, myc antikoerper, MYC proto-oncogene, bHLH transcription factor antikoerper, v-myc myelocytomatosis viral oncogene homolog antikoerper, nucleolar protein 3 (apoptosis repressor with CARD domain) antikoerper, myelocytomatosis oncogene antikoerper, MYC proto-oncogene, bHLH transcription factor a antikoerper, MYC proto-oncogene, bHLH transcription factor L homeolog antikoerper, MYC proto-oncogene, bHLH transcription factor S homeolog antikoerper, v-myc myelocytomatosis viral oncogene homolog (avian) antikoerper, MYC proto-oncogene, bHLH transcription factor b antikoerper, CG10798 gene product from transcript CG10798-RB antikoerper, MYC antikoerper, LOC100136746 antikoerper, Nol3 antikoerper, Myc antikoerper, myca antikoerper, myc.L antikoerper, myc.S antikoerper, mycb antikoerper
Hintergrund
Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates
Molekulargewicht
60 kDa
Gen-ID
4609
NCBI Accession
NP_002458
UniProt
P01106
Pathways
p53 Signalweg , Zellzyklus , Sensory Perception of Sound , Transition Metal Ion Homeostasis , Mitotic G1-G1/S Phases , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus , Warburg Effekt
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