Nanog Antikörper (AA 137-141)
-
- Target Alle Nanog (NANOG) Antikörper anzeigen
- Nanog (NANOG) (Nanog Homeobox (NANOG))
-
Bindungsspezifität
- AA 137-141
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Nanog Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Spezifität
- The antibody detects endogenous level of total Nanog protein.
- Aufreinigung
- Affinity purified
- Immunogen
- Peptide sequence around AA 137-141 (K-Q-V-K-T) derived from Nano g Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product NANOG Primärantikörper
-
-
- Applikationshinweise
- Western blotting: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
- Target
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Andere Bezeichnung
- Nanog (NANOG Produkte)
- Synonyme
- 2410002E02Rik antikoerper, ENK antikoerper, ecat4 antikoerper, NANOG antikoerper, hacp antikoerper, wu:fd19e04 antikoerper, wu:fd20a07 antikoerper, zgc:193933 antikoerper, Nanog homeobox antikoerper, nanog homeobox antikoerper, Nanog antikoerper, NANOG antikoerper, nanog antikoerper
- Hintergrund
- Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to enter into S phase and proliferation
- Molekulargewicht
- 42 kDa
- Gen-ID
- 79923
- NCBI Accession
- NP_079141
- UniProt
- Q9H9S0
- Pathways
- Stem Cell Maintenance
-