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MAP2K4 Antikörper (AA 352-356)
MAP2K4
Reaktivität: Human, Maus, Ratte
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-MAP2K4 Antikörper
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Target
Alle MAP2K4 Antikörper anzeigen
MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
Bindungsspezifität
Alle Epitope für MAP2K4 Antikörper
AA 352-356
Reaktivität
Alle Reaktivitäten für MAP2K4 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für MAP2K4 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MAP2K4 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MAP2K4 Antikörper
Dieser MAP2K4 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MAP2K4 Antikörper
Western Blotting (WB)
Spezifität
The antibody detects endogenous levels of total MAP2K4 protein.
Aufreinigung
Affinity purified
Immunogen
Peptide sequence around AA 352-356 (E-S-K-R-P) derived from Human MAP2K4. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Discover our top product MAP2K4 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Western blotting: 1:500-1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Details zu MAP2K4
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Target
MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
Andere Bezeichnung
MAP2K4 (MAP2K4 Produkte )
Synonyme
JNKK antikoerper, JNKK1 antikoerper, MAPKK4 antikoerper, MEK4 antikoerper, MKK4 antikoerper, PRKMK4 antikoerper, SAPKK-1 antikoerper, SAPKK1 antikoerper, SEK1 antikoerper, SERK1 antikoerper, SKK1 antikoerper, Sek1 antikoerper, Serk1 antikoerper, MKK4A-l antikoerper, map2k4 antikoerper, zgc:136500 antikoerper, jnkk antikoerper, mek4 antikoerper, mkk4 antikoerper, sek1 antikoerper, jnkk1 antikoerper, serk1 antikoerper, xmek2 antikoerper, mapkk4 antikoerper, prkmk4 antikoerper, 142758_at antikoerper, CG9738 antikoerper, CT27508 antikoerper, D-MKK4 antikoerper, DMKK4 antikoerper, Dmel\\CG9738 antikoerper, JNKK2 antikoerper, Mpk4 antikoerper, SEK1/MKK4 antikoerper, dMKK4 antikoerper, dMkk4 antikoerper, hep antikoerper, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antikoerper, ATMEK4 antikoerper, ATMKK4 antikoerper, F19C24.26 antikoerper, F19C24_26 antikoerper, MAP KINASE KINASE 4 antikoerper, mitogen-activated protein kinase kinase 4 antikoerper, MKK4B antikoerper, zgc:194486 antikoerper, mitogen-activated protein kinase kinase 4 antikoerper, mitogen-activated protein kinase kinase 4a antikoerper, MAP kinase kinase 4 antikoerper, mitogen activated protein kinase kinase 4 antikoerper, mitogen-activated protein kinase kinase 4b antikoerper, MAP2K4 antikoerper, Map2k4 antikoerper, map2k4a antikoerper, map2k4 antikoerper, Mkk4 antikoerper, MKK4 antikoerper, map2k4b antikoerper
Hintergrund
SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflamatory cytokines (1-3). Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261, respectively. Like MEK, SEK is a dual-specificity protein kinase that phosphorylates SAPK/JNK at a conserved T*PY* site in its activation loop (4). Phosphorylation by Akt at Ser80 inhibits SEK1 and suppresses stress-activated signal transduction
Molekulargewicht
44 kDa
Gen-ID
6416
NCBI Accession
NP_003001
UniProt
P45985
Pathways
MAPK Signalweg , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , Activation of Innate immune Response , Toll-Like Receptors Cascades , BCR Signaling
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