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CCDC39 Antikörper (AA 651-750)

CCDC39 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872343
  • Target Alle CCDC39 Antikörper anzeigen
    CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
    Bindungsspezifität
    • 15
    • 8
    • 2
    • 1
    AA 651-750
    Reaktivität
    • 31
    • 23
    • 14
    • 9
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCDC39 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 15
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Cow,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CCDC39
    Isotyp
    IgG
    Top Product
    Discover our top product CCDC39 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CCDC39 (Coiled-Coil Domain Containing 39 (CCDC39))
    Andere Bezeichnung
    CCDC39 (CCDC39 Produkte)
    Synonyme
    4921507O14Rik antikoerper, AI447426 antikoerper, AI844750 antikoerper, D3Ertd789e antikoerper, b2b1304Clo antikoerper, b2b1735Clo antikoerper, RGD1306277 antikoerper, CILD14 antikoerper, FAP59 antikoerper, coiled-coil domain containing 39 antikoerper, flagellar associated protein antikoerper, Ccdc39 antikoerper, CCDC39 antikoerper, ccdc39 antikoerper, FAP59 antikoerper
    Hintergrund

    Synonyms: CCD39_HUMAN, Ccdc39, Coiled-coil domain-containing protein 39.

    Background: Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia, reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

    Gen-ID
    339829
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