Corin Antikörper (AA 165-245)

Produktnummer ABIN872360

Produktdetails anti-Corin Antikörper

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Bindungsspezifität: AA 165-245

Reaktivität: Human, Ratte, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Corin Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Ratte, Schaf

Homologie: Mouse,Dog,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Corin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Corin Antikörper (ABIN872360)

Miyazaki, Nishizawa, Kambayashi, Ito, Noda, Terasawa, Kato, Miyamura, Shiogama, Sekiya, Kurahashi, Fujii: "Increased levels of soluble corin in pre-eclampsia and fetal growth restriction." in: Placenta, Vol. 48, pp. 20-25, (2017) (PubMed).

Sari, Rufaut, Jones, Sinclair: "Characterization of Ovine Dermal Papilla Cell Aggregation." in: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).

Details zu Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Andere Bezeichnung: Corin (CORIN Produkte)

Synonyme: CORIN antikoerper, CG2105 antikoerper, Dmel\\CG2105 antikoerper, SP75 antikoerper, LOC559109 antikoerper, AV273130 antikoerper, Lrp4 antikoerper, ATC2 antikoerper, CRN antikoerper, PEE5 antikoerper, TMPRSS10 antikoerper, corin, serine peptidase antikoerper, CG2105 gene product from transcript CG2105-RC antikoerper, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) antikoerper, corin antikoerper, CORIN antikoerper, Corin antikoerper, LOC559109 antikoerper

Hintergrund:

Synonyms: CRN, ATC2, Lrp4, PEE5, TMPRSS10, Atrial natriuretic peptide-converting enzyme, Corin, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, Transmembrane protease serine 10

Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

Gen-ID: 10699

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones