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KDM4A Antikörper (AA 75-155)

KDM4A Reaktivität: Maus ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872374
  • Target Alle KDM4A Antikörper anzeigen
    KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
    Bindungsspezifität
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-155
    Reaktivität
    • 50
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 41
    • 9
    • 2
    Kaninchen
    Klonalität
    • 42
    • 10
    Polyklonal
    Konjugat
    • 33
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDM4A Antikörper ist unkonjugiert
    Applikation
    • 22
    • 20
    • 11
    • 9
    • 8
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human JMJD2A/KDM4A
    Isotyp
    IgG
    Top Product
    Discover our top product KDM4A Primärantikörper
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
    Andere Bezeichnung
    JMJD2A (KDM4A Produkte)
    Synonyme
    JMJD2A antikoerper, JHDM3A antikoerper, JMJD2 antikoerper, TDRD14A antikoerper, D4Ertd222e antikoerper, Jmjd2 antikoerper, Jmjd2a antikoerper, mKIAA0677 antikoerper, lysine demethylase 4A antikoerper, lysine-specific demethylase 4A antikoerper, lysine (K)-specific demethylase 4A antikoerper, KDM4A antikoerper, LOC100228023 antikoerper, Kdm4a antikoerper
    Hintergrund

    Synonyms: JMJ2A, JmjC domain containing histone demethylation protein 3A, JmjC domain-containing histone demethylation protein 3A, JMJD2, jumonji C domain containing histone demethylase 3A, Jumonji domain containing 2, Jumonji domain containing 2A, Jumonji domain containing protein 2A, Jumonji domain-containing protein 2A, KDM4A, KDM2A_HUMAN, KIAA0677, Lysine-specic demethylase 4A.

    Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

    Pathways
    Warburg Effekt
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