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TBCD Antikörper (AA 401-500)

TBCD Reaktivität: Maus WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872398
  • Target Alle TBCD Antikörper anzeigen
    TBCD (Tubulin Folding Cofactor D (TBCD))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 1
    AA 401-500
    Reaktivität
    • 11
    • 1
    • 1
    Maus
    Wirt
    • 9
    • 2
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    Dieser TBCD Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TBCD/Beta tubulin cofactor D
    Isotyp
    IgG
    Top Product
    Discover our top product TBCD Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TBCD (Tubulin Folding Cofactor D (TBCD))
    Andere Bezeichnung
    Beta tubulin cofactor D (TBCD Produkte)
    Synonyme
    SSD-1 antikoerper, tfcD antikoerper, 2310057L06Rik antikoerper, A030005L14Rik antikoerper, mKIAA0988 antikoerper, tubulin folding cofactor D antikoerper, tubulin-specific chaperone d antikoerper, TBCD antikoerper, Tbcd antikoerper
    Hintergrund

    Synonyms: Beta tubulin cofactor D, Beta-tubulin cofactor D, KIAA0988, SSD 1, SSD-1, SSD1, tbcd, TBCD_HUMAN, tfcD, Tubulin folding cofactor D, Tubulin specic chaperone D, Tubulin-folding cofactor D, Tubulin-specic chaperone D.

    Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.

    Gen-ID
    6904
    Pathways
    Cell-Cell Junction Organization
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