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Nidogen Antikörper (AA 1001-1100)

NID Reaktivität: Maus, Ratte ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872401
  • Target Alle Nidogen (NID) Produkte
    Nidogen (NID)
    Bindungsspezifität
    • 2
    • 1
    • 1
    AA 1001-1100
    Reaktivität
    • 11
    • 2
    • 2
    Maus, Ratte
    Wirt
    • 10
    • 1
    Kaninchen
    Klonalität
    • 10
    • 1
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Nidogen Antikörper ist unkonjugiert
    Applikation
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Cow,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Entactin
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Nidogen (NID)
    Andere Bezeichnung
    Nidogen (NID Produkte)
    Synonyme
    BEST:CK00552 antikoerper, CG12908 antikoerper, CT32053 antikoerper, Dmel\\CG12908 antikoerper, ndg antikoerper, Nidogen/entactin antikoerper, Ndg antikoerper
    Hintergrund

    Synonyms: Ent, Entactin 1, Entactin, NID 1, NID, NID-1, Nid1, NID1_HUMAN, Nidogen enactin, Nidogen 1, Nidogen, Nidogen-1, NID1_HUMAN.

    Background: Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is a highly conserved member of the Nidogen family, which also includes Nidogen-2. Nidogen-2 has a high level of N- and O-glycosylation, and it interacts with Collagens Type I and IV and Perlecan at a comparable level to Nidogen. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation. Nidogen also cooperates with Laminin 1 to regulate b-casein expression.

    Gen-ID
    4811
    UniProt
    P14543
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