NEK1 Antikörper (AA 301-400)

Produktnummer ABIN872417

Produktdetails anti-NEK1 Antikörper

Target: NEK1 (NIMA-Related Kinase 1 (NEK1))

Bindungsspezifität: AA 301-400

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEK1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NEK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NEK1 Antikörper (ABIN872417)

Yeo, Becherel, Luff, Graham, Richard, Lavin: "Senataxin controls meiotic silencing through ATR activation and chromatin remodeling." in: Cell discovery, Vol. 1, pp. 15025, (2016) (PubMed).

Details zu NEK1

Target: NEK1 (NIMA-Related Kinase 1 (NEK1))

Andere Bezeichnung: NEK1 (NEK1 Produkte)

Synonyme: D8Ertd790e antikoerper, kat antikoerper, NY-REN-55 antikoerper, SRPS2 antikoerper, SRPS2A antikoerper, ATNEK1 antikoerper, F20D21.32 antikoerper, F20D21_32 antikoerper, NIMA-RELATED KINASE1 antikoerper, NIMA-related serine/threonine kinase 1 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 1 antikoerper, NIMA related kinase 1 antikoerper, NIMA-related kinase 1 antikoerper, NIMA-related serine/threonine kinase 1 antikoerper, Nek1 antikoerper, NEK1 antikoerper

Hintergrund:

Synonyms: SRPS2, SRTD6, SRPS2A, NY-REN-55, Serine/threonine-protein kinase Nek1, Never in mitosis A-related kinase 1, NimA-related protein kinase 1, Renal carcinoma antigen NY-REN-55, NEK1, KIAA1901

Background: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Implicated in the control of meiosis (By similarity). Involved in cilium assembly. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death.

Gen-ID: 4750

UniProt: Q96PY6