SRGN Antikörper (AA 61-158)

Produktnummer ABIN872475

Dieses Anti-SRGN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SRGN in ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für SRGN Antikörper (AA 61-158) (ABIN872475)

Target: SRGN (serglycin (SRGN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRGN Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SRGN Antikörper

Bindungsspezifität: AA 61-158

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Serglycin/SRGN Polyclonal Antibody

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SRGN

Target: SRGN (serglycin (SRGN))

Andere Bezeichnung: SRGN

Hintergrund:

Synonyms: Chondroitin sulfate proteoglycan core protein, Cytolytic granule proteoglycan core protein, Hematopoetic proteoglycan core protein, Mastocytoma proteoglycan core protein, P.PG, PG19 core protein, Pgsg, Platelet proteoglycan core protein, platelet proteoglycan protein core, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG, PRG, PRG1, PROTEOGLYCAN 1, proteoglycan 1, secretory granule, Proteoglycan 10K core protein, Proteoglycan peptide core protein, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE, secretory granule proteoglycan 1, Secretory granule proteoglycan core protein, Serglycin, serglycin proteoglycan, Sgc, Srgn, SRGN_HUMAN.

Background: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Gen-ID: 5552

Pathways: Maintenance of Protein Location