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IL-6 Antikörper (AA 51-150)

IL6 Reaktivität: Human, Maus, Schwein, Kaninchen, Rind (Kuh) WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN872547
  • Target Alle IL-6 (IL6) Antikörper anzeigen
    IL-6 (IL6) (Interleukin 6 (IL6))
    Bindungsspezifität
    • 19
    • 18
    • 17
    • 15
    • 15
    • 14
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 193
    • 129
    • 75
    • 24
    • 20
    • 20
    • 14
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    Human, Maus, Schwein, Kaninchen, Rind (Kuh)
    Wirt
    • 196
    • 88
    • 68
    • 16
    • 4
    • 3
    • 2
    Kaninchen
    Klonalität
    • 219
    • 155
    • 1
    Polyklonal
    Konjugat
    • 199
    • 59
    • 28
    • 12
    • 12
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-6 Antikörper ist unkonjugiert
    Applikation
    • 269
    • 138
    • 104
    • 59
    • 52
    • 51
    • 40
    • 40
    • 37
    • 31
    • 25
    • 25
    • 19
    • 19
    • 14
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Rind (Kuh), Human, Maus, Schwein, Kaninchen
    Homologie
    Cow,Sheep,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IL-6
    Isotyp
    IgG
    Top Product
    Discover our top product IL6 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Chen, Wu, Jiang, Zhou, Wang, Yao, Yi, Gou, Yang: "Isoliquiritigenin inhibits the growth of multiple myeloma via blocking IL-6 signaling." in: Journal of molecular medicine (Berlin, Germany), Vol. 90, Issue 11, pp. 1311-9, (2012) (PubMed).

  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Andere Bezeichnung
    IL-6 (IL6 Produkte)
    Synonyme
    BSF2 antikoerper, HGF antikoerper, HSF antikoerper, IFNB2 antikoerper, IL-6 antikoerper, Il-6 antikoerper, ILg6 antikoerper, Ifnb2 antikoerper, il6 antikoerper, CHIL-6 antikoerper, interleukin 6 antikoerper, interleukin-6 antikoerper, IL6 antikoerper, Il6 antikoerper, il-6 antikoerper, IL-6 antikoerper
    Hintergrund

    Synonyms: HGF, HSF, BSF2, IL-6, IFNB2, Interleukin-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6

    Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

    Gen-ID
    3569
    UniProt
    P05231
    Pathways
    TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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